再我今年3月施打完9價人類乳突疫苗,至今半年沒有感覺到任何不良症狀,先來強調人類乳凸疫苗就是所謂的「子宮頸疫苗」,但由於4價、9價可以施打在男性身體上,並且該病毒HPV會引起陰道癌、陰莖癌、口腔癌、頭頸癌等等,應該專業的翻譯為「人類乳突疫苗」才對。
由於前陣子看完了免疫學,又經過疫苗的親身試驗,於是上網尋找了一下國外文獻及過內感染科雜誌,很不巧的人類乳突在國內並沒有被太大重視,相關的資料都非常舊,已目前4價、9價的試驗統計發現,和9價的免疫人體推論都顛覆以往的醫療資訊,都是在目前網路上沒有任何醫師詳細指出,或是引用哪些單位做出來的報告。
- 鄭舒倖醫師的2018.5學術PDF刊載:https://nics.org.tw/download_datax.php?id=1615
從上面PDF仔細研究,已經有很大的統計數字能證明施打疫苗能降低4價、9價所包含的類型的病毒引起症狀,以及感染愛滋的病人也能產生抗體,觀察到口腔HPV有減少現象,可惜肛門癌、陰莖癌並沒有降低感染率,但發現愛滋病患在第7個月抗體和第2年所產生抗體濃度相當都有97%-100%,在澳洲數據發現施打疫苗大大降低男性感染HPV,從愛滋身上來檢視,如果免疫細胞都被HIV感染並且得到適當控制,在配合上疫苗,理學推論在正常人身上一定產生抗體的,並且能降低感染率,這是因為正常人的身體免疫系統並沒有被攻擊,所以推論疫苗的體液性免疫和細胞性免疫一定能啟動作用(這兩類免疫有點複雜這邊不說,可以去買免疫學的書來看一本才600元,最基礎的很容易懂),對照澳洲的男性施打就能知道。
我知道一定有人說,你又不是醫生,或是學感染科畢業的,憑什麼斷定,又非常巧的在上個月美國FDA就發出重大新聞說:「依據4價9價的大型統計能預防88%口腔癌、陰道癌、生殖器癌、外陰、陰道前病變的持續性感染。」
According to the CDC, every year about 14 million Americans become infected with HPV; about 12,000 women are diagnosed with and about 4,000 women die from cervical cancer caused by certain HPV viruses. Additionally, HPV viruses are associated with several other forms of cancer affecting men and women.
Gardasil, a vaccine approved by the FDA in 2006 to prevent certain cancers and diseases caused by four HPV types, is no longer distributed in the U.S. In 2014, the FDA approved Gardasil 9, which covers the same four HPV types as Gardasil, as well as an additional five HPV types. Gardasil 9 was approved for use in males and females aged 9 through 26 years.
The effectiveness of Gardasil is relevant to Gardasil 9 since the vaccines are manufactured similarly and cover four of the same HPV types. In a study in approximately 3,200 women 27 through 45 years of age, followed for an average of 3.5 years, Gardasil was 88 percent effective in the prevention of a combined endpoint of persistent infection, genital warts, vulvar and vaginal precancerous lesions, cervical precancerous lesions, and cervical cancer related to HPV types covered by the vaccine. The FDA’s approval of Gardasil 9 in women 27 through 45 years of age is based on these results and new data on long term follow-up from this study.
我們要有關念知道,體內有病毒存在如果和平共處當然沒事,就好像袍疹病毒、水痘、感冒,這些病毒都是清除不掉的,萬一有天人的免疫力下降這些病毒就會伺機跑出來感染人的正常細胞,皮膚出現異常面積紅斑會痛,這種外顯症狀能清楚了解我生病了,可是HPV不同他被感染皮膚毫無症狀、無痛,這也就是等到異常出血,或是出現生殖器疣才知道我感染了,在很多文獻很多能被感染都能自癒,被免疫系統清除,只有少數的人會持續性感染,這持續性感染要到數年才會發生癌變,屆時發現也來不及措施醫療時機。
感染過HPV病毒到底能不能被清除掉? 根據我研究的體液性免疫 IGg 體液免疫,照學理是可以的,可是病毒很狡猾它會跑會躲起來,讓體異性免疫找不到它,類似水泡、流感,以為我們吃抗生素透過腸道吸收IgM清除水痘、流感,以為病毒不見了,其實病毒都還是在體內並沒有消滅掉,只要病毒沒有發揮出外顯症狀,或是體液性免疫裏的中合作用把其他細胞保護不被病毒感染,甚至是吞噬殺死病毒體,這樣就達到了治療作用。要知道一個病毒傳染力最強時候就是要有「皮膚上的症狀:疣、水泡、體液、口水、血」,當要傳染給另一個人時候就得視「病毒量」的多寡是否能造成「致病機轉」。又有人會問:那如何知道體液、口水、血液有沒有病毒?這個問題就是接種疫苗,讓身體的抗體保持著,而身體的記憶性B細胞,也會有記憶性,當再次受到感染就能釋放抗體來抵抗病毒,所以疫苗是有時效性的,這就是為什麼6月時候麻疹疫情一直擴大原因,因為60年代的人他們打的疫苗已經過了15年失效了,身體上的抗體效價非常低,所以導致麻疹。這邊也要知道並非打了疫苗就是無敵,因為身上的任何免疫都是需要透過胰臟、骨隨、胸等等來分泌所這些器官都必須要休息,也就是正常的作息,還又營養才能充分製造這些免疫分子,再來適當的運動能加速血液代謝讓免疫球能運作的更好,還有別讓自己感冒。
祝大家身體健康
美國 FDA 9價疫苗是用男性27-45
The U.S. Food and Drug Administration today approved a supplemental application for Gardasil 9 (Human Papillomavirus (HPV) 9-valent Vaccine, Recombinant) expanding the approved use of the vaccine to include women and men aged 27 through 45 years. Gardasil 9 prevents certain cancers and diseases caused by the nine HPV types covered by the vaccine.
“Today’s approval represents an important opportunity to help prevent HPV-related diseases and cancers in a broader age range,” said Peter Marks, M.D., Ph.D., director of the FDA’s Center for Biologics Evaluation and Research. ”The Centers for Disease Control and Prevention has stated that HPV vaccination prior to becoming infected with the HPV types covered by the vaccine has the potential to prevent more than 90 percent of these cancers, or 31,200 cases every year, from ever developing.”
According to the CDC, every year about 14 million Americans become infected with HPV; about 12,000 women are diagnosed with and about 4,000 women die from cervical cancer caused by certain HPV viruses. Additionally, HPV viruses are associated with several other forms of cancer affecting men and women.
Gardasil, a vaccine approved by the FDA in 2006 to prevent certain cancers and diseases caused by four HPV types, is no longer distributed in the U.S. In 2014, the FDA approved Gardasil 9, which covers the same four HPV types as Gardasil, as well as an additional five HPV types. Gardasil 9 was approved for use in males and females aged 9 through 26 years.
The effectiveness of Gardasil is relevant to Gardasil 9 since the vaccines are manufactured similarly and cover four of the same HPV types. In a study in approximately 3,200 women 27 through 45 years of age, followed for an average of 3.5 years, Gardasil was 88 percent effective in the prevention of a combined endpoint of persistent infection, genital warts, vulvar and vaginal precancerous lesions, cervical precancerous lesions, and cervical cancer related to HPV types covered by the vaccine. The FDA’s approval of Gardasil 9 in women 27 through 45 years of age is based on these results and new data on long term follow-up from this study.
Effectiveness of Gardasil 9 in men 27 through 45 years of age is inferred from the data described above in women 27 through 45 years of age, as well as efficacy data from Gardasil in younger men (16 through 26 years of age) and immunogenicity data from a clinical trial in which 150 men, 27 through 45 years of age, received a 3-dose regimen of Gardasil over 6 months.
The safety of Gardasil 9 was evaluated in about a total of 13,000 males and females. The most commonly reported adverse reactions were injection site pain, swelling, redness and headaches.
The FDA granted the Gardasil 9 application priority review status. This program facilitates and expedites the review of medical products that address a serious or life-threatening condition.
The FDA granted approval of this supplement to the Gardasil 9 Biologics License Application to Merck, Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.
The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.